

Episode 231 -- June 2025 -- Part 1 AFP: American Family Physician
Jun 16, 2025
Explore the intricacies of acute monoarthritis, detailing its causes and treatment options. Delve into the challenges of adverse drug reaction reporting and the push for better practices in healthcare. Learn about the careful management of antiplatelet drugs to minimize bleeding risks, especially pre-surgery. Discover the disparities in opioid therapy access and effective pain management. Finally, examine the controversial treatment of lukanumab for Alzheimer's, focusing on its risks and the importance of informed decision-making.
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Key Causes and Examination Points
- Acute monoarthritis commonly arises from osteoarthritis, gout, pseudogout, septic arthritis, Lyme arthritis, and other causes.
- Joint examination focusing on effusion and passive range of motion helps distinguish intra-articular from periarticular conditions.
Use Joint Fluid Analysis Wisely
- Use joint aspiration with fluid analysis, including cell count and crystal analysis, to clarify monoarthritis diagnosis.
- Synovial fluid WBC counts can distinguish non-inflammatory, septic, and crystalline arthritis.
Boost Drug Reaction Reporting
- Combine education with tools like ADR reporting forms and reminder cards to triple adverse drug reaction reports.
- Embed ADR reporting into workflows, such as hospital discharge forms, to remove reporting friction.