1) Guillain-Barré syndrome vs. CIDP and 2) progressive myoclonic encephalopathies. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Erik Ensrud interviews Dr. Pieter van Doorn about his paper on Guillain-Barré syndrome. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Harlequin syndrome. In the next part of the podcast Dr. Alberto Espay interviews Dr. Berge Minassian for part 1 on progressive myoclonic encephalopathies for our Lesson of the Week. The participants had nothing to disclose except Drs. van Doorn and Espay.Dr. van Doorn receives research support from the Prinses Beatrix Fonds, the GBS-CIDP Foundation International and from Baxter biopharmaceutics.Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.