
Oncotarget
Oncotarget’s Top 10 Papers Published in 2023 (Crossref Data)
Feb 15, 2024
Discover the latest research in oncology with Crossref's Top 10 Oncotarget papers of 2023, covering topics like angiogenesis inhibition in HNSCC, prognostic index for gastric cancer, crosstalk in triple negative breast cancer, and current approaches in systemic AL amyloidosis.
05:26
Episode guests
Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Hikota Hayashi, Yohei Sasaki, Koki Kawakami, Ryoji Hyakudomi, Tetsu Yamamoto, and Yoshitsugu Tajima
Mikhail V. Blagosklonny, M.D.
Md Maksudul Alam, Janmaris Marin Fermin, Mark Knackstedt, Mackenzie J. Noonan, Taylor Powell, Landon Goodreau, Emily K. Daniel, Xiaohua Rong, Tara Moore-Medlin, Alok R. Khandelwal, and Cherie-Ann O. Nathan
Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross, and Abirami Sivapiragasam
Maroun Bou Zerdan, Lewis Nasr, Farhan Khalid, Sabine Allam, Youssef Bouferraa, Saba Batool, Muhammad Tayyeb, Shubham Adroja, Mahinbanu Mammadii, Faiz Anwer, Shahzad Raza, and Chakra P. Chaulagain
Karly Smrekar, Artem Belyakov and Kideok Jin
Anqi Shao and David M. Owens
Diana Monsivais, Sydney E. Parks, Darshan S. Chandrashekar, Sooryanarayana Varambally, and Chad J. Creighton
Enyuan Shang, Trang Thi Thu Nguyen, Mike-Andrew Westhoff, Georg Karpel-Massler, and Markus D. Siegelin
Gaurav Chakravorty, Suhail Ahmad, Mukul S. Godbole, Sudeep Gupta, Rajendra A. Badwe, and Amit Dutt
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Quick takeaways
- Everolimus inhibits angiogenesis in HNSCC by downregulating STAT3/HIF-1α/VEGF pathway.
- A novel inflammation-based prognostic index predicts survival outcomes in gastric cancer patients.
Deep dives
Understanding Mechanisms of Everolimus in TP53 Mutant HNSCC
Everolimus downregulates stat 3 HIF-1 alpha, VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma. The authors from LSU Health Sciences Center sought to investigate the mechanism for everolimus induced inhibition of TP53 mutant HNSCC.
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