In this episode we discuss:

How endotoxin drives inflammation and stress while downregulating our metabolism
Why alcoholic fatty liver disease isn’t all that different from non-alcoholic fatty liver disease
The protective effects of saturated fats in NAFLD
How endotoxin and polyunsaturated fats can cause NAFLD
Nutrient deficiencies that contribute to energy failure and NAFLD

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-67-endotoxin-and-pufa-as-primary-causes-of-fatty-liver-disease-nafld-part-5/

Timestamps:

3:57 – the role of endotoxin in NAFLD

23:43 – how endotoxin drives inflammation and stress while downregulating our metabolism

30:35 – research looking at endotoxin as the cause of NAFLD

38:30 – how endotoxin mediates alcoholic liver disease and the protective effects of saturated fats

44:56 – endotoxin and other damaging factors in the larger context of NAFLD

52:52 – the role of PUFA in NAFLD

1:12:05 – the contrasting effects of saturated fats and PUFA in alcohol-induced liver damage

1:24:22 – how nutrient deficiencies can cause energy failure and drive NAFLD

1:34:57 – how alcohol causes fatty liver and why alcoholic liver disease doesn’t vary considerably from NAFLD

1:38:49 – other factors that contribute to energy failure and drive NAFLD, including psychological stress, fasting, low-carb diets, low-calorie diets, excessive exercise protective effects of saturated fats

R.I.P. Jane Greer (1953-2025)