72. A New NAD+ Deep Dive: Energy, Aging, Supplements, and NAD IVs

In this episode, Dr. Jones talks again with Dr. Paul Anderson, naturopathic doctor, researcher, and teacher. He joined the podcast last year to talk about cholesterol and lipid labs. This time the focus is on NAD (Nicotinamide Adenine Dinucleotide) and why it matters for your health.

They explain what NAD does in the body, especially for energy, brain function, and recovery. You’ll hear how NAD levels drop as we age, how alcohol and medications can drain it faster, and the different ways the body makes NAD on its own.

Dr. Anderson also talks about today’s options, from supplements like NMN, NR, and niacinamide to IV therapy. He shares when IVs make sense, when oral forms might be enough, and what to know about side effects and safety, including the common question about NAD and cancer.

This is a straight talk about NAD, what’s real and what’s hype, and how it can support energy, recovery, and long-term wellness.

📌 Dr. Paul Anderson

Dr. Anderson is an esteemed educator and clinician in integrative and naturopathic medicine, focusing on complex infectious, chronic, and oncologic illnesses, with over three decades of clinical experience. He founded Advanced Medical Therapies for cancer and chronic diseases in Seattle, Washington, and still collaborates with various clinics and hospitals. He has held positions at multiple medical schools, including Professor of Pharmacology and Clinical Medicine at Bastyr University. He has authored several books and articles and is actively involved in continuing medical education through online platforms and conferences.

🔗 Learn more about Dr. Paul Anderson

Website: https://dranow.com

Instagram: www.instagram.com/draonline/

Connect with Dr. Greg Jones

Instagram: @doctorjones_doctorjones 

Enovative Wellness Center: https://enovativewellness.com/ 

🔬 Timestamps
00:00 – Welcome back and introduction

02:35 – What NAD is and why it matters

06:00 – Real benefits vs. hype around NAD

10:49 – Why NAD levels drop

12:27 – How aging and stress affect NAD

18:18 – How the body makes its own NAD

22:10 – How NAD gets into cells

28:39 – NAD precursors and how they work

37:39 – Can you test NAD levels?

44:23 – Using tests to guide treatment

47:42 – IV therapy vs. oral supplements

51:29 – Using NAD for health and recovery

55:41 – IV nicotinamide riboside explained

01:01:26 – Side effects and safety concerns

01:11:22 – CD38 and its role in NAD decline

01:14:36 – Do NAD patches actually work?

01:16:26 – Subcutaneous injections vs. IV therapy

01:19:56 – Where NAD therapy is headed

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Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations