Wits & Weights | Fat Loss, Nutrition, & Strength Training for Lifters Managing GLP‑1 Side Effects for Weight Loss Without Losing Muscle (Justin Silver) | Ep 358
Aug 8, 2025
Justin Silver, a serial entrepreneur and founder of SymptoGuard, shares his insights on managing the side effects of GLP-1 drugs like Ozempic. He reveals his father's harrowing experience with these medications, highlighting why many users quit despite successful weight loss. They discuss the most common side effects that hinder progress, the concept of 'food noise,' and how specific lifestyle changes can minimize discomfort. Justin also emphasizes the importance of maintaining protein intake and introduces SymptoGuard as a solution to alleviate these challenges.
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GLP‑1 Use Is Already Widespread
- One in seven Americans are now on GLP‑1 drugs and many struggle with unspoken issues.
- Philip Pape warns over half quit within a year and side effects often derail training and protein intake.
Side Effects Are A Major Discontinuation Cause
- Justin Silver says side effects rank second in why people stop GLP‑1 therapy.
- Injection frequency is the top reason, especially due to needle fear and frustration.
A 62‑Year‑Old Lost 100 Pounds, Then Suffered
- Justin Silver recounts his 62‑year‑old father losing 100 pounds on Ozempic but suffering severe nausea, dizziness, and fainting.
- Doctors prescribed many supplements, and he ended up taking 19 pills every morning before Justin created a combined solution.