The Proof with Simon Hill Everything you need to know about metabolic health | Metabolic Health Masterclass
Episode #329. Boost metabolic health and prevent disease with expert insights from an all-star lineup of scientists. Learn key strategies for improving metabolic health, including metabolic flexibility, muscle health, and the critical roles of diet and exercise in preventing type 2 diabetes and fatty liver disease.
In this episode, you’ll hear from a distinguished panel of specialists including applied exercise physiologist Inigo San Millan, PhD; skeletal muscle expert Don Layman, PhD; type 2 diabetes authority Roy Taylor, PhD; dietitian and researcher Andrea Glenn, PhD, RD; nutrition scientist Alan Flanagan, PhD; nutrition scientist and endocrinologist Christos Mantzoros MD, DSc, PhD; and physician and researcher Richard Johnson, MD.
Specifically, we discuss:
- Intro (00:00)
- What is Metabolic Health (01:35)
- Metabolic Health, Mitochondria, Defining 'Metabolise', Metabolic Flexibility (07:02)
- The Importance of Skeletal Muscle for Metabolic Health (20:03)
- Exercise for metabolic health ****Zone 2 (28:36)
- Twin Cycle Hypothesis (56:45)
- Understanding the Personal Fat Threshold (01:08:15)
- Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor (01:17:08)
- Are DASH, Nordic, Mediterranean, and Portfolio diets good for preventing and managing diabetes? (01:36:46)
- Understanding Non-Alcoholic Fatty Liver Disease and Its Development (01:42:39)
- The Science of Hepatic Fat Oxidation (01:49:37)
- Consequences and Effects of Fatty Liver Disease (01:55:14)
- Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (02:00:42)
- Combination of Fructose and Saturated fat on Metabolic Health (02:13:21)
- Type of fat and its effect on Metabolic Health (02:17:35)
- What cause Metabolic Health: fat or fructose (02:24:01)
- New Fat Storage Mechanisms - Personal Fat Threshold (02:27:50)
- Modern Techniques for Accurate Body Fat Measurement (02:31:52)
- Health metabolic biomarkers (02:36:51)
- Ectopic fat (02:38:19)
- Fat storage and metabolic health (02:39:10)
- Evolutionary Insights into Human Fat Storage (02:42:02)
- Fatty Liver Disease (02:45:46)
- Outro (2:57:46)
Connect with today’s guests and listen to their previous episodes at the links above.
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Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
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