Core IM | Internal Medicine Podcast

#6 The Wonderful World of Albumin: Mind the Gap segment

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Jan 3, 2018
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INSIGHT

Albumin Dosage Origins

  • The recommended albumin dosage for SBP (1.5g/kg on day one, 1g/kg on day three) comes from a 1990s study.
  • This study showed reduced renal failure and mortality, despite better antibiotics not improving mortality previously.
ANECDOTE

Anecdote: High Albumin Dose

  • Steve Liu recounts a conversation with a hepatologist who had spoken to Dr. Sort.
  • Dr. Sort's reasoning for the high albumin dose was to ensure a noticeable effect, although it's considered somewhat arbitrary.
INSIGHT

Albumin-Crystalloid Equivalence

  • The equivalence of albumin to crystalloid is approximately 1 unit of albumin to 1 liter of crystalloid.
  • However, this conversion is based on an uncited claim and may not be entirely accurate.
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