Dr. Matt and Dr. Mike's Medical Podcast

Integumentary System

4 snips
Oct 25, 2018
Dive into the fascinating world of the integumentary system! Explore how the skin functions as a protective shield and its vital role in immune response. Learn about melanocytes and the science behind skin color and hair, including evolutionary insights on whiskers. The hosts share anecdotes about UV radiation and its impact on health, while unraveling the intricacies of skin structure, from the epidermis to the dermis. With humor and expertise, they bring the complexities of our skin to life!
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INSIGHT

Multifunctional Integumentary System

  • The integumentary system functions as a barrier, immune component, temperature regulator, UV protector, sensory organ, vitamin D producer, and aesthetic feature.
  • It keeps pathogens and water in and out while enabling absorption of nutrients and detection of environmental stimuli.
INSIGHT

Epidermal Layers and Cornification

  • The epidermis is mainly composed of keratinocytes arranged in layers transitioning from live basal cells to dead corneum cells.
  • The process of keratinocyte maturation through the layers is called cornification, providing skin strength and waterproofing.
INSIGHT

Stratum Corneum Barrier Role

  • The stratum corneum has multiple layers of dead keratin-filled cells held together by filagrin acting as glue.
  • Hydrophobic lipids between cells prevent water loss and block pathogens, ensuring the skin's barrier function.
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