This Week in Startups

Next Unicorns: Developing drugs to extend dog lifespans with Loyal CEO Celine Halioua | E1799

Aug 30, 2023

01:05:15

Snipd AI

Celine Halioua, CEO of Loyal developing drugs to extend dog lifespans, discusses developing drugs for dogs as a model for life extension in humans, genetic issues in dog breeds, the potential profitability of developing life extension drugs for dogs, and the power of the placebo effect in drug trials.

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Quick takeaways

Studying dogs as a model for life extension research can yield valuable insights into improving human health and lifespan, as dogs share similar age-related diseases with humans.

Loyal, a biotech startup, aims to develop life extension treatments for dogs by taking advantage of the potential market and revenue generated by dog medications, presenting a loyal customer base for life extension treatments.

Developing drugs for dogs as a pathway to FDA approval is faster and more affordable, making it an efficient route for researching and developing life extension drugs.

Deep dives

Using Dogs as a Translational Model for Life Extension

The podcast episode explores the use of dogs as a model for life extension research. By studying the genetics, environment, and diseases found in dogs, researchers can gain valuable insights into improving human health and lifespan. Dogs share similar age-related diseases with humans, such as cancer, osteoarthritis, and dementia, making them a suitable model for testing potential life extension drugs. Additionally, FDA approval for life extension drugs in dogs is more affordable and faster, making it an efficient pathway for research and development.

Introduction

2min

Exploring Life Extension through Dog Studies

7min

Blue light glasses, health coaching, and developing drugs to extend dog lifespans

4min

Developing Life Extension Drugs for Dogs

10min

Genetic issues in dog breeds and the regulatory path for lifespan-extending drugs

4min

The Power of the Placebo Effect

12min

Start-up Design and Cognitive Decline in Dogs

3min

Challenging Minds and Determining Biotech Company Value

16min

Challenges of Deep Tech and Inspiration from SpaceX

6min

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Today’s show:

Loyal CEO and Founder Celine Halioua joins Jason to discuss developing drugs that delay dog aging (10:19), lessons learned as a solo founder (49:34), and much more!

Time stamps:

(0:00) Loyal CEO Celine Halioua joins Jason

(1:43) The human dream of achieving life extension

(4:37) Celine’s background

(8:48) Fount - Get $500 off at https://fount.bio/twist

(10:19) Why Celine decided to start with a focus on dogs

(16:43) Wegovy, Ozempic, and the category of drugs that Loyal is developing

(20:44) Breaking down how the drugs work and the consequences of selective breeding

(24:21) LinkedIn Jobs - Post your first job for free at https://linkedin.com/unicorn

(25:36) Stem cell therapy and the placebo effect

(33:29) Environmental factors to consider in drug development

(37:05) The path to commercialization