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Incubation

Smallpox: Gone but Not Forgotten

Sep 7, 2023
Discover the history and impact of smallpox, from the folk practice of variolation to Edward Jenner's invention of the smallpox vaccine. Learn about the origin of the term 'vaccine' and the legacy of Jenner. Explore the audacious plan to eradicate smallpox and the ongoing efforts to eradicate diseases. Plus, hear about the Arexv vaccine preventing lower respiratory disease in older adults.
26:41

Podcast summary created with Snipd AI

Quick takeaways

  • Edward Jenner invented the smallpox vaccine by using cowpox to confer immunity against smallpox, revolutionizing the field of immunization.
  • The successful application of ring vaccination in Sierra Leone set a precedent for global efforts that ultimately led to the eradication of smallpox.

Deep dives

Vaccination to Protect Older Adults from RSV Infection

Orexv, a respiratory syncytial virus (RSV) vaccine, adjuvanted, is proven to be 82% effective in preventing lower respiratory disease from RSV in adults over 60 years old. It is especially effective in those with underlying conditions like asthma, diabetes, COPD, or chronic heart failure. However, it does not protect everyone, and individuals with severe allergies to its ingredients should not receive the vaccine. While common side effects include injection site pain, fatigue, muscle pain, headache, and joint pain, the benefits of vaccination outweigh the risks, making it a crucial prevention measure for older adults.

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