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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

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Advancements in Genomic Technologies

This chapter explores cutting-edge genomic technologies that enhance the study of genetic diseases, highlighting the use of massively parallel reporter assays (MPRA) and automation. It discusses the evolution of RNA sequencing techniques, including single-cell methods that utilize unique barcoding for precise cell analysis. The chapter emphasizes collaborative methodologies that expand research capabilities, allowing for in-depth exploration of genetic implications in brain disorders.

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