Welcome to the metabolism masterclass!
Dr. Ben Bikman (Ph.D Professor BYU), a powerhouse in metabolism science, joins Dave to expose the truth about insulin resistance—the silent epidemic fueling obesity, chronic disease, and low energy. Forget the outdated calorie-counting nonsense (it doesn’t work)—Dr. Bikman reveals how your hormones, not just your diet, control your metabolism and what you can do to reset it fast.
From debunking diet myths to uncovering why some people can eat 400 grams of carbs and never gain fat (hint: it’s not what you think), this episode unpacks the real science of fat storage, energy, and optimal health. Get ready for mind-blowing insights, metabolic hacks, and a new way to think about food, fasting, and longevity.
What You’ll Learn:
• The #1 driver of insulin resistance—and why most doctors miss it
• Why eating more fat (yes, really) could be the key to reversing metabolic dysfunction
• How fasting, cold therapy, and red light impact your metabolism
• The truth about carbs, seed oils, and why some people can’t gain fat
• How to tell if insulin resistance is wrecking your energy & health
Resources:
• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
• Benjamin’s new book How Not To Get Sick : https://a.co/d/aADlMWv
• Benjamin’s YouTube Page – https://www.youtube.com/@benbikman
• 2025 Biohacking Conference: https://biohackingconference.com/2025
• Danger Coffee: https://dangercoffee.com
• Dave Asprey’s Website: https://daveasprey.com
• Dave Asprey’s Linktree: https://linktr.ee/daveasprey
• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com
• Own an Upgrade Labs: https://ownanupgradelabs.com
• Upgrade Labs: https://upgradelabs.com
• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com
SPONSORS:
-Lumiram | Go to http://healthlighting.com/dave to save 10% on your order.
-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.
Timestamps:
00:00 Trailer
00:52 Introduction to Dr. Benjamin Bikman
02:20 The Battle Against Conventional Dietetics
04:12 Understanding Insulin Resistance
06:29 The Two Paths to Insulin Resistance
10:19 Fasting and Metabolic Health
14:11 Insulin and Cognitive Enhancement
18:16 Identifying Insulin Resistance
30:12 The Role of Insulin in Fat Storage
42:04 Understanding Glucose and Insulin Dynamics
42:26 The Role of Exercise in Glucose Regulation
42:54 AMPK and Muscle Contraction
45:21 Calories In, Calories Out Debate
46:15 The Myth of Calorie Counting
50:13 Ketosis and Metabolic Rate
51:14 Intermittent Fasting and Muscle Preservation
55:21 Insulin Resistance and Ketogenic Diets
01:02:04 Circadian Rhythm and Insulin Sensitivity
01:08:08 Environmental Toxins and Insulin Resistance
01:13:03 The Impact of Seed Oils on Insulin Resistance
01:19:22 Final Thoughts and Resources
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