Dr Glenn McConell chats with Professor Claude Bouchard about Genetics and exercise in health and performance. He recently retired at 82 yrs from the Louisiana State University Pennington Biomedical Research Center. He had made an amazing contribution with an H index of 191 and 173,000 citations!! (Google scholar).
0:00. Introduction
1:06. Got Covid19 then went flying fishing!
3:38. How got into genetics research
5:40. Working out the role of genetics before could measure DNA easily
11:05. Using physiology to assist with the genomic pursuit
12:57. Complex traits are influenced by 100s to 1000s of variants
14:36. How got to the HERITAGE study
18:15. Genetics re sedentary cardiorespiratory fitness and trainability
23:46. Genome, proteome, transcriptome and biology
27:49. Epigenetics and training responses.
29:49. Incredible changes in technologies over his career
32:58. High and low capacity runners (rodent studies)
36:56. Do very good endurance athletes start off high capacity runners?
40:03. “Responders” and “non responders”
41:30. Get out and exercise, don’t blame your genes
42:28. Ability to improve health with ex unrelated to trainability Insulin sensitivity etc
44:02. “Non responders” still see beneficial effects of exercise
47:30. Variability of responses to exercise with cancer
51:50. Correlation between initial health and improvements in health with exercise?
53:31. Where’s the field heading?
Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
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