Calcium Ion Related Fatigue

The calcium ion related fatigue is more localized and causes an interference effect with cross bridging between actinomycin. Those are the proteins that are responsible for muscle contraction. And we could go a very tiny little step further and say that this effect is going to be much more prevalent in the highest threshold motion muscle fibers because they have fewer mitochondria, they're less able to remove calcium ions once they're kind of placed into the cytoplasm.