Worms will live longer as well through intermittent fasting. But that t turns out to act using the same dafto, insolent, siggling foxo transcription factor pathway. So other than not reproducing as much, what is it that deft who does to the worm to make it live longer? Sarry: "It wasn't just ocidiv stress reduction. It was a lot of things"
Aging -- everybody does it, very few people actually do something about it. Coleen Murphy is an exception. In her laboratory at Princeton, she and her team study aging in the famous C. Elegans roundworm, with an eye to extending its lifespan as well as figuring out exactly what processes take place when we age. In this episode we contemplate what scientists have learned about aging, and the prospects for ameliorating its effects -- or curing it altogether? -- even in human beings. Coleen Murphy received her Ph.D. in biochemistry from Stanford University, and is currently Professor in the Department of Molecular Biology and the Lewis-Sigler Institute of Integrative Genomics at Princeton. Home page at the Lewis-Sigler Institute Lab web page Princeton Profile Google Scholar publication page Twitter
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