27min chapter

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Episode 168: Alessio Fasano discusses celiac disease and gluten-related disorders

STEM-Talk

CHAPTER

Unveiling the Secrets of Gut Health and Aging

This chapter takes listeners through the journey of Dr. Alicia Fasano, from her interest in pediatrics and gastroenterology to the serendipitous discoveries in studying bacteria pathogenesis, including the zonula occludens toxin. It explores the implications of these findings on vaccine trials and the physiological mechanisms behind inducing diarrhea. Additionally, the chapter delves into the discovery of zonulin, its role in gut permeability and the investigation of celiac disease as a systemic disorder with diverse manifestations and its link to immune diseases and lifestyle factors affecting aging-related gut issues.

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