Is the Immune Escape of Homacron a Good Idea?

There's been a long standing discussion in the evolutionary biology community about what that does to the severity of viruses. The most famous eriment was the release of maxomatosis, a disease of rabbits caused by maxomo virus in australia. And indeed, that started out as an exceedingly virulent virus and did evolve to become less harmful. There is also a mechanistic consideration that seems to be true in flue viruses and might be true also for omicron which is that replicating deep in the lungs is a different property from replicating further up the respiratory tract.