Episode 13 - In the Lab: Dr Coombs? Who is DAT? | Direct Coombs Test
Bloody Minded
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Understanding the Direct Coombs Test
This chapter explores the intricate laboratory processes involved in performing a Direct Coombs Test, essential for diagnosing hemolysis by detecting antibodies on red blood cells. It discusses the critical steps such as cell washing, application of monoclonal antibodies, and the evaluation of agglutination results, emphasizing the significance of accurate interpretation. The chapter also compares manual and automated methodologies while highlighting the complexities and potential errors in the testing process.
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