There's really no practical way to measure autophagy. I remember reading a while back that there was some potential utility for exogenous ketones to helping people avert the so-called low carb flu. We know that if you take exogenous ketone acutely within hours, within minutes, even, you will be up regulating these enzymes and this transporters. When your body is finally keto adapted or when your body is producing its endogenous ketones because your low on carbs and your liver is turning all the fats into ketones, your cells, your muscles, your brain, your heart, they're already treatment tablets.