In this episode we discuss:
- Whether you should be concerned about high LDL or high cholesterol on a low-carb diet
- The validity of the Lean Mass Hyper-Responder (LMHR) Phenotype and Lipid Energy Model proposed by Dave Feldman
- The metabolic state that drives the Lipid Energy Model
- How the "Lean Mass Hyper-Responder" and Lipid Energy Model support the Bioenergetic view of cardiovascular disease
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide
Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-115-lmhr-and-the-lipid-energy-model-implications-for-metabolism-and-hormones
Timestamps:
0:00 – intro
1:14 – what is the Lean Mass Hyper-Responder (LMHR) phenotype
3:33 – how the Lipid Energy Model challenges the mainstream dogmatic view linking high cholesterol levels to heart disease
6:33 – the protective effects of cholesterol and why it does not cause heart disease, despite being necessary for atherosclerosis
9:49 – the distinction between Lean Mass Hyper-Responders and those with high cholesterol levels in the context of metabolic dysfunction
15:10 – what is the Lipid Energy Model
22:10 – how the body adapts to a lack of carbohydrates, leading to elevated cholesterol levels
27:22 – the hormonal and metabolic state underlying the Lean Mass Hyper-Responder phenotype
32:21 – how adding carbohydrates lowers cholesterol levels in those who don't have metabolic dysfunction at a cellular level
37:11 – whether Lean Mass Hyper-Responders are at increased risk of cardiovascular disease
42:00 – why the Lean Mass Hyper-Responder phenotype isn't ideal: stress and low thyroid function
51:10 – the parallels between the lipid energy model and physiological insulin resistance