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“Zombie” Senescent cells may play HUGE role in LIVING LONGER, Here's How: | 22 - Natalia Mitin

The Optispan Podcast with Matt Kaeberlein

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Measuring Cellular Senescence and Immune Longevity

This chapter explores the evolution of assessing cellular senescence and immune system health over the past decade, introducing the Sapir-X test for evaluating biological age. It highlights the significance of immune longevity scores and the interplay between immune function and senescent cells, while also addressing T-cell metrics and the effects of treatments like Everolimus. The discussion delves into the complexities of autophagy in T-cells, its regulation in aging, and implications for immune responses and chronic inflammation.

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