Understanding the Importance of Postprandial Glucose

Question: Why should postprandial blood glucose be kept under 140 milligrams per deciliter? Short Answer: When blood glucose rises above 140 mg/dL, this is the approximate point at which it spills into the polyol pathway at a greater-than-normal rate, which represents a suboptimal state of metabolism that is likely to hurt antioxidant status and compromise detoxification pathways as well as the recycling of vitamin K and folate. It must be kept in mind that a healthy person will adapt to glycemic loads they consume regularly. Thus, a one-time spike above 140 mg/dL should never be used to conclude anything whatsoever. Only repeated spikes above this level with repeated consumption of the same glycemic load over several days to several weeks should be used as a cause for concern.

This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

https://chrismasterjohnphd.substack.com/p/questions-on-blood-glucose-and-oxalate

In that batch of free episodes you will also find the answer to this question:

• How can I protect against oxalates?

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This snippet is from the April 12, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

• What Causes Hypercholesterolemia and Does It Matter?

• How to Reverse Coronary Calcification?

• How to do a comprehensive nutritional screening

• How long after eating improperly cooked egg whites should I wait to take biotin?

• Is the extrusion process as harmful as some claim?

• How long can one fast before micronutrient deficiencies become an issue?

• Do B vitamins compete with each other for absorption?

• Why is thirst a symptom of diabetes?

• Do I agree with Peter Attia that ApoB should be driven as low as pharmacologically possible?

• During a fast, does the body break down muscle?

• How do you rest and refeed your brain?

• Why would someone have high RBC magnesium but low serum magnesium?

• GLA deficiency?

• Should we eat for our ethnicity?

• How convincing are polyphenol studies?

• Can coronary calcium be driven by oxalate?

• Citrulline for vasodilation

• How to reduce catabolism

• Rapid-fire run-through of orphaned questions from the submission contest, including a detailed look at Nadia’s thyroid numbers

Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-april

Access the show notes, transcript, and comments here.