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The Importance of Fibrinogen in Hemostasis
This chapter discusses the role of fibrinogen in forming stable clots and promoting healing. It explores a cohort study that examines fibrinogen levels in patients admitted for bleeding and the impact of fibrinogen replacement. The chapter also introduces the cryostat 1 feasibility study and the CRYOSTAT-2 trial, which investigate the timely administration and effectiveness of cryoprecipitate in improving fibrinogen levels and reducing mortality.