The Role of NAMPT in NAD Production

The reason that the salvage pathway declines with age is because of this one key enzyme. NAMPT actually recycles nicotinamide and converts into NMN, which then gets converted back into NAD. There's been studies that have been done and they've demonstrated that you get around a 50% decrease in this enzyme between the ages of 45 and 60. Many sort of diseases and issues that are associated with NAD decline are actually because of a reduction in this enzyme. So why not restore it back to that? Yes indeed.