
281: Nerd Lab: How Dr. George Brooks Revolutionized our Understanding of Lactate
Fast Talk
The Role of Lactate in Cancer Pathogenesis
This chapter discusses the process of increased glucose uptake within a cell, leading to upregulation of glycolytic enzymes and decreased mitochondrial activity. It explains how the downregulation of mitochondria prevents the use of lactate as fuel and leads to its accumulation, with implications for cancer and metabolism.
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