Immunology for the Rheumatologist: NETs in Lupus
ACR Journals On Air
Neutrophils and Lupus: Unraveling the Connection
This chapter presents a detailed case study of a young woman with lupus and preclinical atherosclerosis, emphasizing the role of neutrophils in the disease's pathophysiology. It explores the formation of neutrophil extracellular traps (NETs), their impact on autoimmune processes, and their potential as indicators for disease flares. Additionally, the chapter highlights genetic factors and environmental triggers that may influence NET formation in lupus patients.
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