Polyunsaturated Fatty Acids Are Toxic, Right?

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If you exclusively feed people polyunsaturated fatty acids, they go into ketosis and it burns off the HNE. There's one animal model problem with that: in excess, these fats are acutely toxic. They did a couple of human experiments where they fed people a lot of polyunsaturated fats to try and get them into ketosis. And they all got nausea, right? And nausea is a sign that you're eating a toxin, essentially.

Today, Paul interviews Tucker Goodrich, Wall Street technology extraordinaire and independent researcher, and Jeff Nobbs, co-founder and CEO of Zero Acre Farms. They take a deep dive into the epidemic of seed oil consumption. They examine conflicting arguments, and then explain why seed oils are likely making humans fat, diabetic, and causing atherosclerosis.

A note from Paul: Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.

Time Stamps:

00:08:14 Podcast begins

00:13:55 What are seed oils and why are they bad for us?

00:23:30 Ancestral consistency of seed oils and linoleic acid

00:42:40 How are seed oils processed?

00:51:40 Should we worry about trans fats?

00:56:40 Let’s talk about HNE and PUFAs

01:13:10 Endocannabinoids

01:30:40 Are seed oils inflammatory?

00:01:43 Diverticulosis

01:47:20 Seed oils & blindness

01:48:45 Closing remarks about linoleic acid