TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease
This Week in Neuroscience
00:00
Gut Origins of Alpha-Synuclein Pathology
This chapter explores the hypothesis that the pathology of alpha-synuclein in Parkinson's disease originates in the gut, examining its prion-like properties and propagation mechanisms. It discusses research methodologies, the relevance of artificial models, and the quest to understand how misfolded proteins lead to neurodegeneration in the brain.
Transcript
Play full episode
