#390: Muscle, Mitophagy, and Longevity: How Urolithin A Supports Healthy Aging and Athletic Performance With Brad Currier, PhD
LONGEVITY with Nathalie Niddam
Mitopure safety and bioavailability
Dr. Brad reviews Mitopure as an FDA-GRAS tested urolithin A formulation and its human safety profile.
Today, I'm joined by Dr. Brad Currier, Manager of Clinical Trials at Timeline Nutrition and an expert in the world of muscle and aging research. Brad is on the cutting edge of mitochondrial science, and in this episode, he helps us unravel the mysteries of why some 80-year-olds are still crushing it in the gym while others struggle to get up the stairs. We dive into his fascinating research on mitophagy—our bodies' system for recycling dysfunctional mitochondria—and what it means for muscle health, strength, and vibrant aging.
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Episode Timestamps:
Episode start … 00:00:00
What is Mitophagy? Why It Matters as We Age ... 00:04:53
Mitophagy in Athletes vs. General Population ... 00:07:15
Urolithin A and Why Most People Can't Make It ... 00:12:12
What Mitopure Does: Mitophagy and Biogenesis ... 00:24:10
Key Study: Strength Gains in Middle-Aged Adults ... 00:26:43
Dose Guidance: 500mg vs. 1g ... 00:31:39
Anti-Inflammatory Effects and Immune Health ... 00:33:07
Benefits Beyond Muscle: Skin, Immunity, Brain ... 00:35:01
Weightlifter Study: Performance in Trained Athletes ... 00:40:34
Mitopure for Recovery and User Experiences ... 00:46:41
How to Use Mitopure: Timing, Dosage, Consistency ... 00:52:54
Protein, Creatine, and Mitopure: The Basics Stack ... 00:53:41
Recovery, Cycling, and How Soon Benefits Appear ... 00:58:44
Debunking Myths: Pomegranate, Antioxidant, Athletes Only ... 01:10:26
Mitopure vs. Generic Urolithin A: Safety Concerns ... 01:13:39
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