Advancements in CAR-T Cell Therapy for Autoimmune Diseases

The chapter explores innovative strategies in CAR-T cell therapy for autoimmune diseases, focusing on the challenges of current therapies targeting all CD19 positive cells and the need for precision treatments. They discuss the potential of allogeneic CAR-T cells, catcher T cells, and targeting specific antigens to address limitations and enhance therapy efficacy. The conversation also touches on ongoing clinical trials, the suitability of CAR T cell therapy for different rheumatic diseases, and the future possibilities for precision immunotherapy in treating autoimmune diseases.