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April 2025: Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis

American Journal of Psychiatry Audio

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Navigating Anticholinergic Burden in Schizophrenia

This chapter explores the intricate relationship between anticholinergic medications and cognitive function in patients with schizophrenia. It highlights the potential cognitive impairments associated with these medications while emphasizing the necessity of balancing their benefits and drawbacks on an individual basis. The discussion also calls for more rigorous research to better assess the impact of anticholinergic burden and to inform better treatment strategies for patients with psychosis.

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