Tranexamic Acid (TXA) in GI Bleeds: Uncertain Effectiveness

They discuss the evidence for using tranexamic acid (TXA) in gastrointestinal (GI) bleeds, highlighting the pattern of small, low-quality studies suggesting a benefit, followed by larger, higher-quality trials showing no superiority of TXA over placebo. The results were not particularly exciting, and they conclude that the best available evidence suggests that TXA should not be used in patients with GI bleeds.