The Role of FOXO3 in DNA Repair

With the NAD it's a fuel for PARB and my understanding of the way PARB works is that well it's technical name is polyadp ribose, polymerase. So yeah, that's exactly what happens. The FOXO3 as a transcription factor actually turns on the enzymes that the PARB would set up to work. And just go and go to what you asked before as I realized I didn't mention it and sort of link between FOXO3 and NAD is that as well as FOXO3 being directly activated through various types of stress. It can also be activated indirectly via NAD so what happens is they have an ejector stress, NAD goes up, NAD activates C