2min chapter

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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

CHAPTER

Gene Expression Variants - What Are the Effects of Genetic Variants on Disease?

When I say strong effect, I mean at the level of individual mutations. So you have to think of first the effect of the gene on the disease. What we care about is genes that impact the disease a lot but genetics gives us the full equation. And which genes correlate with disease by a lot are the best places to intervene.

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