The Ratio of Systatin C to Creatinine in the Pitasal Arm

One thing that bugged me about primary analysis is kind of a qualitative analysis where you are saying, all right, we see an association with creatinine, but no association with systatin C. That's obviously a function of sample size and the precision and the confidence intervals. Ideally, what you want to do is have a quantitative quantitatively examined. And so one way to do that is with the ratio. Those ratios were significantly lower in the pitasal arm compared to sephapine. So the the inference is that creatinine was increasing to a significantly greater extent than either of the compared or biomarker.