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The Mitochondrial Link to Mental Illness | Ana Andreazza, PhD | The Metabolic Link Ep.63

The Metabolic Link

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Innovations in Brain Organoids and Mitochondrial Insights

This chapter explores the creation and potential of brain organoids derived from induced pluripotent stem cells, emphasizing their role in studying neurological conditions like bipolar disorder. It highlights advancements in organoid technology, including the incorporation of microfluidics for vasculature development, which enhances nutrient delivery crucial for maturation. Additionally, the chapter examines the interplay between mitochondrial and nuclear DNA, shedding light on their significance in genetic susceptibility to diseases and mitochondrial dysfunctions.

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