Metformin: Benefits and Risks

This chapter explores the dual role of metformin, an anti-diabetic medication, in enhancing insulin sensitivity while discussing its broader applications and significant side effects. It emphasizes the relationship between metformin and essential nutrients, particularly the risk of vitamin B12 deficiency and its impact on mitochondrial function. Additionally, the chapter highlights the metabolic mechanisms activated by metformin, particularly the role of AMPK in energy regulation and its controversial use as a biohacking tool.