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22min chapter
#062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
FoundMyFitness
Exploring Biological Aging and Epigenetics
This chapter investigates the intricacies of biological aging, revealing that individuals can age at different rates despite having the same chronological age. It highlights the significance of biomarkers such as DNA methylation and explores the relationship between epigenetic aging and longevity, including the peculiarities of the Hispanic mortality paradox. Additionally, the chapter emphasizes the potential of epigenetic clocks in understanding health outcomes and aging trajectories, while also discussing the challenges that remain in their clinical application.
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