In today’s episode, MIT computational biologist Manolis Kellis dive into the hidden patterns linking DNA, evolution, and cognition, exploring a potential unifying theory that bridges biology, AI, and the essence of life.
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LINKS MENTIONED:
- Manolis Kellis’s Lab (website): https://compbio.mit.edu/
- Manolis Kellis’s profile: https://web.mit.edu/manoli/
- Curt’s article on language: https://curtjaimungal.substack.com/p/language-isnt-just-low-resolution
- Chiara Marletto on TOE: https://www.youtube.com/watch?v=Uey_mUy1vN0
- Roger Penrose on TOE: https://www.youtube.com/watch?v=sGm505TFMbU
TIMESTAMPS:
00:00 - Introduction
02:05 - The Scope of Biological Unification
06:02 - Biology vs. Physics
09:31 - DNA as Life’s Language
13:45 - The Universal Compatibility of DNA
16:55 - Evolutionary Trade-Offs and Isolation
20:17 - Layers of Abstraction in Biology
24:51 - Beyond DNA: The Role of Histones
30:30 - Protein Folding and Function
35:26 - How Cells Interpret DNA Signals
40:24 - The Creativity of Language and Miscommunication
44:55 - Teaching and Simplification
51:09 - Evolution of Cognition and Centralized Decision-Making
57:35 - Vertical vs. Horizontal Evolution
1:04:20 - Specialization and Society’s Role in Evolution
1:08:50 - The Future of Biological Understanding
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