5 Takeaways From the 2021 CCS H-Referb Guideline

The foundation of medical therapy for H-referb currently consists of quadruple therapy. If patients cannot afford ARNIs or are intolerant to them, you could start an ACE inhibitor or ARB instead. The third thing I want to say is that it's important to initiate standard therapies as soon as possible and titrate every two to four weeks so they can be maximally tolerated over three to six months.