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#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
What Is Single Cell RNA Sequencing?
The genome is enormous. 3.2 billion, you don't want to test that. Instead, you basically use all of these tools that I've talked about already. You generate your top favorite 10,000 hypotheses, and then you go and test all 10,000. And then from what comes out, you can then go to the next step. The third technology is coupling CRISPR perturbations with single cell RNA readouts.
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