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Wellness + Wisdom Podcast
Why Most People Can't Make Urolithin A
Dr. Currier explains gut microbiome loss and poor diets prevent many from converting dietary precursors into urolithin A.
Is mitochondrial decline the hidden blueprint that decides how fast your body ages?
Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out.
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In This Episode, Dr. Brad Currier Uncovers: [01:10] How to Optimize Mitochondrial Health- How our mitochondrial DNA is passed from mothers to children.
- The functions of mitochondria in the human body.
- How our environment affects our mitochondria.
- Why UV radiation from the sun damages proteins in our cells.
- How sedentary lifestyle impact mitochondrial health.
Resources:
[08:35] Intergenerational Mitochondrial Health- How mitochondrial health is impacted by multiple generations that came before us.
- Why we're impacted by seven generations before us, and we impact seven generations after us.
- The importance of nurturing our mitochondrial health.
Resources:
[12:55] The Cause of Aging- What causes faster aging.
- How our cells become unhealthy and age.
- Why our cell turnover slows down as we age.
- How mitochondria break down and impact our energy levels.
Resources:
[16:55] The Importance of Urolithin A- The role of postbiotics in digestion.
- Why we need Urolithin A for optimal health.
- How Urolithin A was discovered.
Resources:
[20:55] You Need to Fix Your Microbiome- Why we have to take supplements to maintain our health.
- How the microbiome blocks production of Urolithin A.
- Why most people's gut microbiome is damaged.
- How our gut microbiome lacks diversity compared.
- How the gut-brain axis is linked to many diseases.
- Why mitochondria can impact different systems of the body.
- The importance of supplementing Urolithin A.
- Why food cannot help us produce more Urolithin A.
- How aging affects protein absorption.
- Why Mitopure is the only clinically proven supplement to activate mitophagy.
- The three phases of the mitochondria's life cycle.
- Why removing cellular residue prevents aging.
- How healthy mitochondria can help us live a better life.
- Why renewing cellular energy requires consistency.
- How mitochondrial health impacts mood and mental health.
- Why Timeline Nutrition continues running new clinical studies.
- How repeated scientific research proves whether something truly works or not.
- Why they publish all of their studies online.
- Why professional athletes have a higher risk of heart attack.
- How exercise is the best tool for health and longevity.
- Why combining Mitopure with exercise increases mitochondrial health.
- How weightlifting helps us create new cells.
- How Brad takes care of his own health.
- Why exercise is the most important tool for him.
- The role of a good diet and sleep in our health.
- Why change can feel counterintuitive at first.
- The importance of allowing ourselves to feel uncomfortable.
- How we can't often know for sure what tools or supplements are best for us.
"Poor quality food and pollutants in our environment ultimately converge on the mitochondria and have an impact on its ability to produce energy. When we have this accumulation of debris in our cells, they don't work as well and they start releasing toxins that impact cells around them. " — Dr. Brad Currier, PhD
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Brad Currier, PhD, is a clinical scientist specializing in mitochondrial health, cellular aging, and metabolic resilience.
With a background in translational research and applied clinical science, Brad focuses on how mitochondria, lifestyle inputs, and environmental stressors influence energy production, longevity, and disease risk.
His work bridges cutting-edge science with real-world application, helping people understand how to protect and optimize their cellular engines for sustained health, performance, and resilience.
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