Innovations in Genetic Research and Personalized Medicine

This chapter explores a research initiative focused on sequencing the genomes of children with rare genetic conditions, emphasizing the shift to patient-derived stem cells for developing personalized therapies. It discusses the advancements in generating induced pluripotent stem cells (iPSCs) and the use of organoids to model diseases, highlighting their potential in drug discovery and treatment prediction. The chapter critiques traditional pharmaceutical practices and showcases a novel approach to screening existing drugs for tailored treatment plans in rare diseases.