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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

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Genes, Mitochondria, and Obesity

This chapter explores the roles of IRX3 and IRX5 genes in lipid metabolism and mitochondrial function, highlighting their impact on energy production and obesity. It further discusses groundbreaking genetic discoveries and potential interventions for reversing obesity through innovative techniques like CRISPR-Cas9.

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