14min chapter

The Curious Clinicians cover image

89 - Tusks & Tumor Suppressors

The Curious Clinicians

CHAPTER

Exploring the Role of P53 in Cancer Prevention and Elephant DNA

Delve into the significance of the P53 protein in preventing cancer, mutations in the TP53 gene leading to cancer development, and the evolutionary advantage of multiple copies of TP53 in elephants for lower cancer rates. The chapter also discusses the potential of introducing TP53 into the human genome through gene editing to prevent cancers and ethical implications associated with such genetic modifications.

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