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Theory & Application of CAR-T Therapy

ACR on Air

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Understanding the Evolution of B Cells and the Impact of Therapies on Memory Cells

Exploration of how B cells adapt and gain potency upon exposure to antigens, along with insights into how therapies like CAR T cell therapy impact antigen-experienced B cells while sparing naive cells. The chapter also touches on the challenges posed by long-lived plasma cells in bone marrow niches, offering a nuanced view of memory B cell deletion.

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