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24. Thrombocytopenia with Dr. Matthew Rendo, MD.

Critical Care Time

CHAPTER

Understanding Thrombocytopenia and Platelet Function

This chapter provides a comprehensive exploration of thrombocytopenia, detailing the role of platelets in the coagulation cascade and their origin from the bone marrow. It covers definitions of mild, moderate, and severe thrombocytopenia, the significance of platelet counts in relation to bleeding risks, and the concept of pseudo thrombocytopenia due to sampling errors and platelet clumping. The discussion extends to the interplay between platelet counts, coagulation factors, and the use of thromboelastography (TEG) for detailed coagulation assessments in various medical scenarios.

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