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Cholesterol, metabolic health and heart disease | Dr Alan Flanagan and Danny Lennon
The Proof with Simon Hill
How Do We Know How Many Lipoproteins Are Atherogenic Than HDL?
The best way to assess the number of not only LDL, but other lipoproteins apart from HDL, is by measuring this APOB lipoprotein B. Now importantly, this doesn't sit on the HDL particle, but it'll be on the LDL, IDLs, LDLs and VLDLs. So there's one of these APOBs on each of those particles. And that refinement in understanding risk over time has essentially highlighted that it's not necessarily the cholesterol content per se of those particles,. But the overall number of those particles, if we have much more APOB containing lipoprotein, that elevates risk.
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