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#453: Nick Gant, PhD – Cognitive Performance: Impact of Caffeine, Nicotine & Creatine (Rebroadcast)

Sigma Nutrition Radio

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Is There a Difference Between Exercise and Chronic Fatigue?

We think the kind of fatigue that accompanies certainly prolonged exercise and it may be the same for prolonged cognitive work is an imbalance of certain neurotransmitters. And most of the consensus is around the brain catacolamine so dopamine and neurodrenaline. We know that these have very high turnover rates when the brain is very active. When they're turning over all the time they tend to become out of whack or depleted, we get a change in excitation and inhibition within the areas where they're required for important neurotransmission. So from study to study we may see a focus on specific characteristics related to fatigue that we're going to try and assess particularly with this study.

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